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Showing posts from January, 2019

Icthyosis/Fish scale disease /Collodion baby Cause Clinical features management

Icthyosis / fish scale disease / collodion baby. It is a genetics- autosomal recessive disorder,  Affecting around 1 in 600,000 people due to  deficiency of the enzyme keratinocyte transglutaminase- Keratinization disorders (hyperkeratosis). Synonane of Collodion baby. a. Fish scale disease. b. collodion  baby. Cause of Collodion baby. Genetics- autosomal recessive disorder. Affecting around 1 in 600,000 people. Basic defect- deficiency of the enzyme keratinocyte transglutaminase- Keratinization disorders (hyperkeratosis). Clinical feature of Collodion baby. - Scanty hair (may be absent). - Ectropion (lower eyelids turned outwards away from the eyeball). - Flat nose or ear. - Eclabium-(O shaped oral orifice)- the turning out of the lips due to the tightness of the membrane. - Extensive scaling of the skin caused by hyperkeratosis. - Very hard, thick, scaly, parchment like skin. - Dry fissur...

Hemolytic disease of the newborn (HDN) Cause Type Clinical features Investigation Management Prevention

Hemolytic disease of the newborn (HDN) Neonatal bleeding due to vitamin K deficiency. K dependent clotting factors are- II, VII, IX, X.

All About Apnea Cause Types Clinical Features Investigation Management

Apnea. Cessation of respiration more than 20 seconds with or without bradycardia and cyanosis is called apnea.